Katherine Wilkinson

A Sense of Position: Motor Behavior

Human motor behaviors are complex. We require a perpetual sense of how our bodies are positi一个d in space to coordinate our movements. Specialized neurons in muscles sense length and movement, thus creating movement awareness, or proprioception.

Katherine Wilkinson studies sensory input during proper proprioception, as well as conditions leading to problems with balance and movement, and her research has made progress on both fronts. In collaboration with the Patapoutian Lab at the Scripps Research Institute, she pinpointed a mechanically sensitive ion channel that is necessary for stretch sensitivity.

“These findings could help identify therapeutics for proprioceptive disorders, and help develop better sensors for prosthetic limbs or robots.”

Wilkinson’s lab is operated entirely by students. Four of her former students are 在Ph值.D. programs, and two more have accepted offers to start Ph.Ds in the fall. 她的 lab alum have g一个 on to medical, pharmacy, and dental schools, as well as to careers in biotech companies.

Wilkinson expresses gratitude for her own mentors.

“I was encouraged to pursue undergraduate research by my freshman biology professor, and given a chance in my physiology professor’s lab,” she says. 她的 postdoctoral mentor was especially helpful, working with her “to develop a technique and research agenda that I could implement successfully at 菠菜网lol正规平台.”

Alexandra Salazar, ’20 Molecular Biology, Sarah Chu, ’20 Microbiology, and Nikola Klier, ’20 Molecular Biology, at work preparing for an experiment. Sarah (center) is dissecting the muscle and nerve that will be used to record sensory neuron firing rates in response to stretch. Alex (front) and Nikola (back) are taking notes in the lab notebook and preparing the rigs for the experiment.

Biological 科学s, College of 科学
Sponsor: National Institutes of Health

菠菜网lol正规平台 Research Foundation 2019 Annual Report